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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CUL3
All Species:
36.06
Human Site:
T442
Identified Species:
52.89
UniProt:
Q13618
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13618
NP_003581.1
768
88930
T442
H
L
A
R
R
L
L
T
N
K
S
V
S
D
D
Chimpanzee
Pan troglodytes
XP_001167451
757
87889
T431
H
L
A
R
R
L
L
T
N
K
S
V
S
D
D
Rhesus Macaque
Macaca mulatta
XP_001109600
746
86448
T420
H
L
A
R
R
L
L
T
N
K
S
V
S
D
D
Dog
Lupus familis
XP_534586
746
86477
T420
H
L
A
R
R
L
L
T
N
K
S
V
S
D
D
Cat
Felis silvestris
Mouse
Mus musculus
Q9JLV5
768
88930
T442
H
L
A
R
R
L
L
T
N
K
S
V
S
D
D
Rat
Rattus norvegicus
Q9JJ31
780
90872
D465
L
T
R
R
L
I
L
D
I
S
A
D
S
E
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512511
642
74121
S330
D
S
E
K
N
M
I
S
K
L
K
T
E
C
G
Chicken
Gallus gallus
XP_422620
768
88957
T442
H
L
A
R
R
L
L
T
N
K
S
V
S
D
D
Frog
Xenopus laevis
Q6DE95
768
88933
T442
H
L
A
R
R
L
L
T
N
K
S
V
S
D
D
Zebra Danio
Brachydanio rerio
NP_955985
766
89011
T440
H
L
A
R
R
L
L
T
N
K
S
V
S
D
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24311
774
89493
K458
V
F
K
Y
I
E
D
K
D
V
F
Q
K
Y
Y
Honey Bee
Apis mellifera
XP_625079
767
89385
L440
H
L
A
K
R
L
L
L
N
K
S
V
S
D
D
Nematode Worm
Caenorhab. elegans
Q17391
777
90217
L448
Y
L
A
K
R
L
L
L
D
K
S
C
S
D
D
Sea Urchin
Strong. purpuratus
XP_001178314
675
78472
L363
H
L
A
K
R
L
L
L
N
K
S
V
S
D
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q94AH6
738
86284
S424
V
K
L
L
A
Y
I
S
D
K
D
L
F
A
E
Baker's Yeast
Sacchar. cerevisiae
P53202
744
86097
S416
I
K
Q
D
L
L
D
S
T
K
L
I
G
L
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.9
97.1
96.8
N.A.
99.4
26.4
N.A.
83.1
99.6
98.5
95.9
N.A.
28.4
77.2
49.6
67
Protein Similarity:
100
98
97.1
96.8
N.A.
99.6
49.4
N.A.
83.3
99.7
99.2
98.3
N.A.
52.4
87.5
69.1
76.9
P-Site Identity:
100
100
100
100
N.A.
100
20
N.A.
0
100
100
100
N.A.
0
86.6
66.6
86.6
P-Site Similarity:
100
100
100
100
N.A.
100
40
N.A.
26.6
100
100
100
N.A.
6.6
93.3
86.6
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
31.3
26.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
54.5
46.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
69
0
7
0
0
0
0
0
7
0
0
7
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
7
0
7
0
% C
% Asp:
7
0
0
7
0
0
13
7
19
0
7
7
0
69
69
% D
% Glu:
0
0
7
0
0
7
0
0
0
0
0
0
7
7
7
% E
% Phe:
0
7
0
0
0
0
0
0
0
0
7
0
7
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
7
% G
% His:
63
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
7
0
0
0
7
7
13
0
7
0
0
7
0
0
7
% I
% Lys:
0
13
7
25
0
0
0
7
7
82
7
0
7
0
0
% K
% Leu:
7
69
7
7
13
75
75
19
0
7
7
7
0
7
7
% L
% Met:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
7
0
0
0
63
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
7
0
0
0
0
0
0
0
0
7
0
0
0
% Q
% Arg:
0
0
7
57
69
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
7
0
0
0
0
0
19
0
7
69
0
75
0
0
% S
% Thr:
0
7
0
0
0
0
0
50
7
0
0
7
0
0
0
% T
% Val:
13
0
0
0
0
0
0
0
0
7
0
63
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
7
0
0
7
0
7
0
0
0
0
0
0
0
7
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _